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Penile Injection Therapy Backgrounder - Penile injection therapy was discovered fortuitously. In 1980, the French physician Ronald Virag reported that during penile surgery, he inadvertently injected an anesthetized patient in the wrong part of the penis with papaverine - a substance derived from the opium poppy. The resulting relaxation of the smooth muscle of the penile arterial walls created an unexpected two-hour erection. This mistake prompted serious research into the use of injectable medications to relieve ED. Around the same time, Giles Brindley, a British physiologist and research scientist, discovered that injecting the drug phenoxybenzamine into the corpora cavernosa of the penis could produce an erection within minutes. At a meeting in Paris in 1984, New York urologist Dr. Adrian Zorgniotti presented his first case studies of self-injection utilizing a combination of papaverine and phentolamine. The latter drug blocks the action of neurotransmitters that cause vasoconstriction, causing the smooth muscles of the penis to relax. Two years later, Japanese researchers presented evidence that injecting the drug prostaglandin E-1 produced powerful erections. Slowly, news of the favorable results with the injectable medication began to spread within the small international community of urologists who were treating ED. Most began utilizing all three (papaverine, phentolamine, and prostaglandin E-1) in what was referred to as "trimix." More Studies, More Seats What are the side effects of sildenafil (Viagra)? In treating men with erectile dysfunction, doctors worry most about heart disease. "Any form of cardiovascular disease is more likely to occur in men who have erectile dysfunction," says Ira Sharlip, MD, a urologist in San Francisco and past president of the Sexual Medicine Society of North America. Media file 2: Vascular disease often associated with diabetes mellitus is found in the majority of men with erectile dysfunction. In these patients, the medications they take for hypertension often exacerbate their erectile dysfunction. When the problem is psychological, the underlying depression or anxiety is what should be treated. buy pfizer cialis online 50mg viagra online without prescription Several medical treatments may help men who have premature ejaculation. Some antidepressants seem to help delay ejaculation, including antidepressants called selective serotonin reuptake inhibitors (SSRIs). These antidepressants are available with your doctor’s prescription. However, the U.S. Food and Drug Administration (FDA) has not approved the use of these medicines to treat premature ejaculation. Also, antidepressants may cause side effects such as nausea, dry mouth and drowsiness. Antidepressants may also decrease your desire to have sex. Your family doctor can help you decide if an antidepressant is right for you. Q. What about the problem of prolonged erection? Arteriography: This test is given to people who are candidates for vascular reconstructive surgery. A dye is injected into the artery believed to be damaged and X-rays are taken. The mind is inspired through physical (touch) and sensory perceptions and it focuses the muscle of the penis to chill out and this improves blood flow to the penis. Prostate resection - minimally invasive - discharge Common causes of ED include diseases that affect blood flow, such as atherosclerosis (hardening of the arteries); nerve diseases, psychological factors, such as stress, depression, and performance anxiety; and injury to the penis. Chronic illness, certain medications and a condition called Peyronie's disease (scar tissue in the penis) can also cause ED. With respect to neurological causes, involvement of any nerve group, either central or peripheral, may lead to erectile dysfunction. Cerebral diseases lead to decreased sexual interest, possibly through over-inhibition of spinal centres. Among patients with spinal cord injury, 95% of those who have upper motor neuron lesions are capable of reflexogenic erections, 25% of patients who have lower motor neuron lesions are capable of psychogenic erections, and more than 90% of patients who have incomplete lesions of either kind retain their erectile function.21 Direct injury to the cavernosal nerve and blood supply commonly occurs during therapy for prostate cancer; erectile dysfunction is present to some extent in 80% of patients so treated, whether by surgery or external beam radiation therapy.22 More drastically, inflatable or rigid penile implants may be fitted surgically. Implants are irreversible and costly. A study presented at the same AUA meeting found that unpadded seats reduce penile blood flow more than padded seats. The width of the padded seats wasn't a factor. Vimax has a top quality and highly effective formula and YES the results are entirely permanent. When you have reached you pinnacle level of enhancement you are free to stop using Vimax Pills.